MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIDES
\mˈɛmbɹɐnˌɒpɹəlˌɪfəɹətˌɪv ɡlˈɒməɹˌuːlə͡ʊnfɹˌɪta͡ɪdz], \mˈɛmbɹɐnˌɒpɹəlˌɪfəɹətˌɪv ɡlˈɒməɹˌuːləʊnfɹˌɪtaɪdz], \m_ˈɛ_m_b_ɹ_ɐ_n_ˌɒ_p_ɹ_ə_l_ˌɪ_f_ə_ɹ_ə_t_ˌɪ_v ɡ_l_ˈɒ_m_ə_ɹ_ˌuː_l_əʊ_n_f_ɹ_ˌɪ_t_aɪ_d_z]\
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Chronic glomerulonephritis characterized histologically by proliferation of mesangial cells, increase in the mesangial matrix, and a thickening of the glomerular capillary walls. The wall thickening is sometimes said to be a result of the interposition of mesangial cytoplasm or matrix between the basement membrane and the endothelium of the capillary wall. It is often divided into types I and II, and sometimes III. Pathogenesis is not well understood, but some types are thought to involve the immune system, with the complement system, in particular, being implicated.
By DataStellar Co., Ltd
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Nearby Words
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