RENAISSANCE MAN

\ɹɪnˈe͡ɪsəns mˈan], \ɹɪnˈe‍ɪsəns mˈan], \ɹ_ɪ_n_ˈeɪ_s_ə_n_s m_ˈa_n]\

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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