COATED VESICLES
\kˈə͡ʊtɪd vˈɛsɪkə͡lz], \kˈəʊtɪd vˈɛsɪkəlz], \k_ˈəʊ_t_ɪ_d v_ˈɛ_s_ɪ_k_əl_z]\
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Vesicles formed when cell-membrane coated pits (COATED PITS, CELL-MEMBRANE) invaginate and pinch off. The outer surface of these vesicles are covered with a lattice-like network of coat proteins, such as CLATHRIN, coat protein complex proteins, or CAVEOLINS.
By DataStellar Co., Ltd
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.