DUNDATHU PINE
\dʌndˈaθuː pˈa͡ɪn], \dʌndˈaθuː pˈaɪn], \d_ʌ_n_d_ˈa_θ_uː p_ˈaɪ_n]\
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By Princeton University
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.