G4 ANTIGEN
\d͡ʒˈiː fˈɔːɹ ˈantɪd͡ʒˌɛn], \dʒˈiː fˈɔːɹ ˈantɪdʒˌɛn], \dʒ_ˈiː f_ˈɔː_ɹ ˈa_n_t_ɪ_dʒ_ˌɛ_n]\
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Cell adhesion molecules that mediate neuron-neuron adhesion and neuron-astrocyte adhesion. They are expressed on neurons and Schwann cells, but not astrocytes and are involved in neuronal migration, neurite fasciculation, and outgrowth. Ng-CAM is immunologically and structurally distinct from NCAM (NEURAL CELL ADHESION MOLECULES).
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.