HRF20
\ˌe͡ɪt͡ʃˌɑːɹˈɛf twˈɛnti], \ˌeɪtʃˌɑːɹˈɛf twˈɛnti], \ˌeɪ_tʃ_ˌɑː_ɹ_ˈɛ_f t_w_ˈɛ_n_t_i]\
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Small glycoproteins found on both hematopoietic and non-hematopoietic cells. CD59 restricts the cytolytic activity of homologous complement by binding to C8 and C9 and blocking the assembly of the membrane attack complex. (From Barclay et al., The Leukocyte Antigen FactsBook, 1993, p234)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.