META AMINOSALICYLIC ACID
\mˈɛtəɹ ɐmˌɪnəsˌalɪsˈɪlɪk ˈasɪd], \mˈɛtəɹ ɐmˌɪnəsˌalɪsˈɪlɪk ˈasɪd], \m_ˈɛ_t_ə_ɹ ɐ_m_ˌɪ_n_ə_s_ˌa_l_ɪ_s_ˈɪ_l_ɪ_k ˈa_s_ɪ_d]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.