GUT SPREAD

\ɡˈʌt spɹˈɛd], \ɡˈʌt spɹˈɛd], \ɡ_ˈʌ_t s_p_ɹ_ˈɛ_d]\
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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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