HOMEOTIC GENES
\hˌə͡ʊmiːˈɒtɪk d͡ʒˈiːnz], \hˌəʊmiːˈɒtɪk dʒˈiːnz], \h_ˌəʊ_m_iː__ˈɒ_t_ɪ_k dʒ_ˈiː_n_z]\
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Highly conserved DNA sequences which have been identified in specific gene transcripts ranging from those of Drosophila melanogaster to mouse and human. Homeobox genes function, in part, to generate DNA-binding proteins with an evolutionary conserved approximately 60-residue sequence (HOMEODOMAIN PROTEINS).
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.