MANOEL SEVERIM DE FARIA

\mˈanə͡ʊl sˈɛvəɹɪm də fˈe͡əɹiə], \mˈanə‍ʊl sˈɛvəɹɪm də fˈe‍əɹiə], \m_ˈa_n_əʊ_l s_ˈɛ_v_ə_ɹ_ɪ_m d_ə f_ˈeə_ɹ_i__ə]\

Definitions of MANOEL SEVERIM DE FARIA

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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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