MK231
\ˌɛmkˈe͡ɪ tˈuːhˈʌndɹədən θˈɜːtiwˈɒn], \ˌɛmkˈeɪ tˈuːhˈʌndɹədən θˈɜːtiwˈɒn], \ˌɛ_m_k_ˈeɪ t_ˈuː_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_i_w_ˈɒ_n]\
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A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
By DataStellar Co., Ltd
