TOMAS DE YRIARTE

\tˈə͡ʊməz dəɹ ˈɪɹa͡ɪ͡ət], \tˈə‍ʊməz dəɹ ˈɪɹa‍ɪ‍ət], \t_ˈəʊ_m_ə_z d_ə_ɹ ˈɪ_ɹ_aɪə_t]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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