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Definition of amputate : 1. To cut off ( a limb or projecting part of the body)
2. To prune or lop off, as branches or tendrils.

Synonyms:

knap, lop off, break off, chip, disrupt, break up, interrupt, cut out, chop off, dismember, cut off, operate on, truncate, cut away

disqualify, exile, deny, reject, disallow, evict, bar, expel, boycott, repudiate, ban, eradicate, blackball, blacklist, relegate, ostracize, eject, renounce, excommunicate, forbid, eliminate, ignore, exclude, banish, disbar, deport, oust, prohibit, extradite, expatriate, proscribe

divide, incise, bisect, sever, sunder, slice, disarticulate, unfix, disintegrate, split, disjoin, estrange, alienate, remove, detach, dissociate, disunite, disassemble, insulate, cut, fragment, break, disaffiliate, axe, disengage, divorce, cleave, part, rend, unglue, halve, separate, dissect, disconnect, rip, excise, disassociate, segregate, uncouple, pare, scissor, unhinge, dismantle

excavate, extricate, withdraw, extract, draw

Usage examples:

• There it became necessary to amputate his leg, and Zahn surrendered what little courage he had left. - "Sketches of the East Africa Campaign", Robert Valentine Dolbey.
• They found that gangrene had already set in, and decided that the only way to save her life was to amputate the foot. - "The First Governess of the Netherlands, Margaret of Austria", Eleanor E. Tremayne.
• Well, says the surgeon, with sudden pleasantness, as he reached after his saw and one of the pick- axes, I must amputate your left leg at once. - "The Orpheus C. Kerr Papers. Series 1", Robert H. Newell.