COMPLEMENTARITY DETERMINING REGION I
\kˌɒmplɪməntˈaɹɪti dɪtˈɜːmɪnɪŋ ɹˈiːd͡ʒən ˈa͡ɪ], \kˌɒmplɪməntˈaɹɪti dɪtˈɜːmɪnɪŋ ɹˈiːdʒən ˈaɪ], \k_ˌɒ_m_p_l_ɪ_m_ə_n_t_ˈa_ɹ_ɪ_t_i d_ɪ_t_ˈɜː_m_ɪ_n_ɪ_ŋ ɹ_ˈiː_dʒ_ə_n ˈaɪ]\
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Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.
Nearby Words
- complementarity
- complementarity determining region
- complementarity determining region 1
- complementarity determining region 2
- complementarity determining region 3
- Complementarity Determining Region I
- complementarity determining region ii
- complementarity determining region iii
- complementarity determining regions
- complementary
- complementary angles