LITTEN'S DIAPHRAGM PHENOMENON

\lˈɪtənz dˈa͡ɪəfɹˌam fɪnˈɒmɪnən], \lˈɪtənz dˈa‍ɪəfɹˌam fɪnˈɒmɪnən], \l_ˈɪ_t_ə_n_z d_ˈaɪ_ə_f_ɹ_ˌa_m f_ɪ_n_ˈɒ_m_ɪ_n_ə_n]\

Definitions of LITTEN'S DIAPHRAGM PHENOMENON

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1898 - American pocket medical dictionary
By Willam Alexander Newman Dorland

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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