MACDONOUGH, THOMAS
\məkdˈɒnʌf], \məkdˈɒnʌf], \m_ə_k_d_ˈɒ_n_ʌ_f]\
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(1783-1825), commodore, served in the Tripoli expedition under Decatur from 1803 to 1804. He gained a celebrated victory over a superior British squadron under Commodore Downie at Plattsburg on Lake Champlain in 1814. The British fleet consisted of sixteen vessels with ninety-five guns and 1000 men, and lost about 200, besides prisoners. The American force consisted of fourteen vessels, carrying eighty-six guns and 850 men, and lost 112 men.
By John Franklin Jameson
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.