REPRESSOR MOLECULES
\ɹɪpɹˈɛsə mˈɒlɪkjˌuːlz], \ɹɪpɹˈɛsə mˈɒlɪkjˌuːlz], \ɹ_ɪ_p_ɹ_ˈɛ_s_ə m_ˈɒ_l_ɪ_k_j_ˌuː_l_z]\
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Proteins which are normally bound to the operator locus of an operon, thereby preventing transcription of the structural genes. In enzyme induction, the substrate of the inducible enzyme binds to the repressor protein, causing its release from the operator and freeing the structural genes for transcription. In enzyme repression, the end product of the enzyme sequence binds to the free repressor protein, the resulting complex then binds to the operator and prevents transcription of the structural genes.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.