HMG 20
\ˌe͡ɪt͡ʃˌɛmd͡ʒˈiː twˈɛnti], \ˌeɪtʃˌɛmdʒˈiː twˈɛnti], \ˌeɪ_tʃ_ˌɛ_m_dʒ_ˈiː t_w_ˈɛ_n_t_i]\
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A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These "ubiquitinated" proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
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