REV PROTEIN
\ɹˈɛv pɹˈə͡ʊtiːn], \ɹˈɛv pɹˈəʊtiːn], \ɹ_ˈɛ_v p_ɹ_ˈəʊ_t_iː_n]\
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Trans-acting nuclear proteins whose functional expression are required for HIV viral replication. Specifically, the rev gene products are required for processing and translation of the HIV gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. rev is short for regulator of virion.
By DataStellar Co., Ltd
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