T4 CELL
\tˈiː fˈɔː sˈɛl], \tˈiː fˈɔː sˈɛl], \t_ˈiː f_ˈɔː s_ˈɛ_l]\
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A critical subpopulation of regulatory T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes, which includes both the helper-inducer (T-LYMPHOCYTES, HELPER-INDUCER) and suppressor-inducer (T-LYMPHOCYTES, SUPPRESSOR-INDUCER) T-cells.
By DataStellar Co., Ltd
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