INCLUSION BODIES
\ɪnklˈuːʒən bˈɒdɪz], \ɪnklˈuːʒən bˈɒdɪz], \ɪ_n_k_l_ˈuː_ʒ_ə_n b_ˈɒ_d_ɪ_z]\
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A generic term for any circumscribed mass of foreign (e.g., lead or viruses) or metabolically inactive materials (e.g., ceroid or Mallory bodies), within the cytoplasm or nucleus of a cell. Inclusion bodies are in cells infected with certain filtrable viruses, observed especially in nerve, epithelial, or endothelial cells. (Stedman, 25th ed)
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.