JACOB AUGUST RIIS

\d͡ʒˈe͡ɪkəb ˈɔːɡəst ɹˈɪa͡ɪz], \d‍ʒˈe‍ɪkəb ˈɔːɡəst ɹˈɪa‍ɪz], \dʒ_ˈeɪ_k_ə_b ˈɔː_ɡ_ə_s_t ɹ_ˈɪ__aɪ_z]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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