COMPARTMENT SYNDROME
\kəmpˈɑːtmənt sˈɪndɹə͡ʊm], \kəmpˈɑːtmənt sˈɪndɹəʊm], \k_ə_m_p_ˈɑː_t_m_ə_n_t s_ˈɪ_n_d_ɹ_əʊ_m]\
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Conditions in which increased pressure within a limited space compromises the circulation and function of tissue within that space. Compartmentation involves mainly the leg but also involved are the forearm, arm, thigh, shoulder, and buttock. Some of the causes of increased pressure are trauma, tight dressings, hemorrhage, and exercise. Sequelae include nerve compression, paralysis, and contracture.
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Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.