FRANKLIN BACHE

\fɹˈaŋklɪn bˈɑːk], \fɹˈaŋklɪn bˈɑːk], \f_ɹ_ˈa_ŋ_k_l_ɪ_n b_ˈɑː_k]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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