GLYZOPHROL
\ɡlˈa͡ɪzəfɹˌɒl], \ɡlˈaɪzəfɹˌɒl], \ɡ_l_ˈaɪ_z_ə_f_ɹ_ˌɒ_l]\
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An alkylating agent having a selective immunosuppressive effect on bone marrow. It has been used in the palliative treatment of chronic myeloid leukemia, but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen. (Merck Index, 11th ed)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.