MK733
\ˌɛmkˈe͡ɪ sˈɛvənhˈʌndɹədən θˈɜːtiθɹˈiː], \ˌɛmkˈeɪ sˈɛvənhˈʌndɹədən θˈɜːtiθɹˈiː], \ˌɛ_m_k_ˈeɪ s_ˈɛ_v_ə_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_i_θ_ɹ_ˈiː]\
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A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL-cholesterol (LIPOPROTEINS, LDL CHOLESTEROL).
By DataStellar Co., Ltd
