SEVERE COMBINED IMMUNODEFICIENCY DISEASE

\sɪvˈi͡ə kəmbˈa͡ɪnd ɪmjˈuːnə͡ʊdfˌɪʃənsi dɪzˈiːz], \sɪvˈi‍ə kəmbˈa‍ɪnd ɪmjˈuːnə‍ʊdfˌɪʃənsi dɪzˈiːz], \s_ɪ_v_ˈiə k_ə_m_b_ˈaɪ_n_d ɪ_m_j_ˈuː_n_əʊ_d_f_ˌɪ_ʃ_ə_n_s_i d_ɪ_z_ˈiː_z]\

Definitions of SEVERE COMBINED IMMUNODEFICIENCY DISEASE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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