WILLEM VAN HAREN

\wˈɪləm vˈan hˈaɹən], \wˈɪləm vˈan hˈaɹən], \w_ˈɪ_l_ə_m v_ˈa_n h_ˈa_ɹ_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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