ADENOID CYSTIC CARCINOMAS
\ˈadənˌɔ͡ɪd sˈɪstɪk kˌɑːsɪnˈə͡ʊməz], \ˈadənˌɔɪd sˈɪstɪk kˌɑːsɪnˈəʊməz], \ˈa_d_ə_n_ˌɔɪ_d s_ˈɪ_s_t_ɪ_k k_ˌɑː_s_ɪ_n_ˈəʊ_m_ə_z]\
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Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.