ABRAM JOSEPH RYAN

\ˈe͡ɪbɹam d͡ʒˈə͡ʊsəf ɹˈa͡ɪən], \ˈe‍ɪbɹam d‍ʒˈə‍ʊsəf ɹˈa‍ɪən], \ˈeɪ_b_ɹ_a_m dʒ_ˈəʊ_s_ə_f ɹ_ˈaɪ_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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