RETENTION OF URINE

\ɹɪtˈɛnʃən ɒv jˈʊ͡əɹɪn], \ɹɪtˈɛnʃən ɒv jˈʊ‍əɹɪn], \ɹ_ɪ_t_ˈɛ_n_ʃ_ə_n ɒ_v j_ˈʊə_ɹ_ɪ_n]\

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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