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Definition of muddle : 1. A number of things of the same kind, ordinarily used or classed together; a collection of articles which naturally complement each other, and usually go together; an assortment; a suit; as, a set of chairs, of china, of surgical or mathematical instruments, of books, etc.
2. A state of being turbid or confused; hence, intellectual cloudiness or dullness.
3. To cloud or stupefy; to render stupid with liquor; to intoxicate partially.
4. To dabble in mud.
5. To make turbid, or muddy, as water.
6. To mix confusedly; to confuse; to make a mess of; as, to muddle matters; also, to perplex; to mystify.
7. To think and act in a confused, aimless way.
8. To waste or misuse, as one does who is stupid or intoxicated.

Synonyms:

piddle, raft, boggle, yap, micturate, fixing, peck, blow, stack, locating, spend a penny, bollix up, hollow, welter, blunder, mare's-nest, mint, mess hall, make, goof up, make water, foul up, sight, gob, heap, flounder, fixture, golf hole, mending, fare, confusion, snafu, trap, localisation, flock, kettle of fish, passel, slew, batch, muckle, throw, puddle, plenty, tidy sum, pickle, hodgepodge, press, maw, repair, jumbal, get by, shift, get along, mismanage, pot, discombobulate, help, mess up, make do, messiness, patchwork, electronic jamming, good deal, gum up, mountain, louse up, hole, fuddle, muff, manage, fumble, limp, addle, smother, fend, dizzy, shuffle, clear, mass, fudge, deal, snarl, muck up, spoil, make out, bewilder, bungle, pass water, pee, fix, mystify, great deal, reparation, thrive, stumble, location, lot, cakehole, correct, urinate, hatful, jam, pee-pee, feelings, bumble, screw up, quite a little, jamming, ball up, relieve oneself, wad, order, mishandle, take a leak, pile, crush, spate, piss, mussiness, disarray, wee, make shift, stagger, disrupt, unsettle, do, mend, localization, befuddle, mickle, wee-wee

fluster, misconstrue, cloud, baffle, mistake, perplex, obscure

difficulty, complexity, intricacy, emergency, perplexity, involvement, quandary, pother, complication, dilemma, predicament, struggle, awkwardness, encumbrance, puzzle

disorganize, convulse, discompose, disarrange, tamper, mix-up, scatter, derange, hash, displace, jumble, swirl, whisk, toss, ruffle, dislocate, mess, confuse, trouble, roil, disturb, roughen, churn, rummage, misplace, meddle, dishevel, botch, capsize, mislay, confound, agitate, tumble, clutter, upset, scramble, rumple, ripple, ferment, perturb, whip, disorder, tousle, blur, muss

Usage examples:

• The two elders were making various absurd inquiries, when Richard sent his chair to the floor, crying, " What a muddle you're in, Rip! - "The Complete Project Gutenberg Works of George Meredith", George Meredith.
• Or wait till Miss Vancourt arrives an' begins to muddle round with the church! - "God's Good Man", Marie Corelli.
• Pearl is not all I have in that muddle! - "Lily Pearl and The Mistress of Rosedale", Ida Glenwood.